A Mexican girl who had been in the US for medical care, her mother, and members of flight and medical crews were on board the plane.
An air ambulance transporting a child who had just completed treatment for a life-threatening condition, her mother and four others, has crashed into a Philadelphia neighbourhood in the United States.
The plane crashed shortly after takeoff just after 6pm (23:00 GMT) on Friday evening, exploding in a fireball that engulfed several homes, videos aired on local TV stations showed.
The incident marked another US aviation disaster after a passenger plane and a military helicopter collided midair in capital Washington, DC, earlier this week.
Jet Rescue Air Ambulance, which operated the Learjet 55, said in a statement: “We cannot confirm any survivors.” It said the plane had four crew members apart from the child and her mother.
All six on board were Mexican citizens, the country’s foreign ministry said in a statement.
The child was being transported home, according to Jet Rescue spokesperson Shai Gold. The flight’s final destination was Tijuana after a stop in Missouri, about 1,800km (1,100 miles) to the southwest.
“The patient had received care from Shriners Children’s Philadelphia and was being transported back to her home country in Mexico on a contracted air ambulance when the crash happened,” said Mel Bower, a spokesman for Shriners Children’s hospital.